University of California San Francisco
About UCSF

Research

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The areas of research at QBI are constantly expanding and include, but are not limited to Structural Biology, Biophysics, Drug Discovery, Synthetic Biology, Bioinformatics, Computational Biology, Bioengineering, Imaging and System Biology.

Biophysics

Biophysics uses the tools of physics to watch biology in action. To visualize what macromolecules like proteins, RNA, or DNA look like, biophysicists use powerful X-rays or electron microscopes. These techniques can define the shape of the molecules.

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Biophysics
BMNC

The Biomedical Micro &;; Nanotechnology Core (BMNC) is envisioned as a nexus point of innovation at the micro- and nanoscale that embodies the mission statement and efforts of QBI

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BMNC
Cell Mapping

The ability of a cell to respond to its environment depends on the actions of the proteins encoded by the DNA in the genome. However, most proteins don't work alone. They work with other proteins in teams called complexes.

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Cell Mapping
Computational Biology

Computational biologists aim to address fundamental and applied questions in biology and biomedicine, by analyzing and modeling biological datasets using sophisticated theoretical and computational techniques.

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Computational Biology
Imaging

QBI at UCSF holds exemplary human and preclinical imaging research services offered by the Department of Radiology and Biomedical Imaging.

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Imaging
Systems Biology

Systems biology is based on the understanding that the whole is greater than the sum of the parts. It is a strongly collaborative discipline and often involves scientists from many areas, including molecular and chemical biology, physics, computer science, engineering and bioinformatics. It involves the quantitative deciphering of complex biological systems using networks at multiple scales.

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Systems Biology
Bioengineering

The health and life sciences are in the midst of a profound revolution. The cross-disciplinary application of new technology and quantitative approaches from engineering, computer science, and physics to the life sciences has fueled fundamental...

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Bioengineering
Drug Discovery

The development of CRISPR technologies has enabled the design of elegant animal models to test the mechanisms of these drugs, and to understand their off-target liabilities.

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Drug Discovery
Nuclear Magnetic Resonance (NMR)

Nuclear Magnetic Resonance (NMR) takes advantage of small changes in the behavior of the nuclei in atoms that allows them to sense their chemical environment.

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Nuclear Magnetic Resonance (NMR)
Structural Biology

Biophysics uses the tools of physics to watch biology in action. To visualize what macromolecules like proteins, RNA, or DNA look like, biophysicists use powerful X-rays or electron microscopes.

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Structural Biology