QBI is about breaking down the walls in academia and creating teams between different sets of scientists working in diverse disciplines to tackle problems that can only be solved by many groups working together. Academic research is often focused on the individual scientist. For example, grants are often awarded to a single investigator, tenure is assessed based on individual achievements, and most awards are given to a single scientist. In fact, if there is significant collaborative work, the contributions of individual investigators, especially younger ones, are often questioned. This structure incentivizes research that is often unnecessarily competitive and siloed. In fact, our current academic system can actually impede discovery. Increasingly, many big breakthroughs in biomedical research require teams to work together, where each group brings something unique but highly complementary to the problem. QBI will lead by example with teams of scientists solving each individual problem – together. Technology, and the data derived from it, is at the heart of collaborative efforts, as QBI scientists are the experts developing experimental and computational tools that can be applied to many biological or biomedical problems. These tools allow for effective connection between the discovery research and clinical worlds, enabling novel therapies for disease.
QBI is about breaking down the walls in academia and creating teams between different sets of scientists working in diverse disciplines to tackle problems ...
The Quantitative Biosciences Institute (QBI) fosters collaborations across the biomedical and the physical ...
The Quantitative Biosciences Institute (QBI) fosters collaborations across the biomedical and the physical sciences, seeking quantitative methods to address pressing problems in biology and biomedicine. Motivated by problems of human disease, QBI is committed to investigating fundamental biological mechanisms, because ultimately solutions to many diseases have been revealed by unexpected discoveries in the basic sciences.
The members of the QBI Executive Committee are experienced scientists and pioneers who are past and present directors of the institute. Their exceptional achievements are a sound but optimistic lense through which they see and guide the institute’s future aspirations.
See MembersBiomolecule Building & Design to interrogate & Engineer Biological Systems
Develops methods for determining macromolecular assemblies structures
Investigates new chemical tools and techniques to perturb biology
Focuses on the structural mechanisms of the Hsp90 molecular chaperone
Uses unbiased, systems approaches to understand complex biological problems
Biomolecule Building & Design to interrogate & Engineer Biological Systems
Develops methods for determining macromolecular assemblies structures
Investigates new chemical tools and techniques to perturb biology
Focuses on the structural mechanisms of the Hsp90 molecular chaperone
Uses unbiased, systems approaches to understand complex biological problems
New platforms for the application of personalized medicine and cancer therapies
Novel chemical tools that interrogates biological processes on a molecular level
Protein shapes and the Environments Affecting Protein Motion
Techniques for acquisition, reconstruction, quantitative analysis of MR imaging
QBI Associate Directors are the face of the future of science. These young scientists are focused on new approaches and ideas, and bring a fresh perspective to the institute and its direction.
See Members 
QBI was originally part of QB3, known as QB3-UCSF. QBI focuses on academic research and fostering collaboration ...
QBI was originally part of QB3, known as QB3-UCSF. QBI focuses on academic research and fostering collaboration between different science disciplines. In March of 2016, QBI became its own institute, and an Organized Research Unit (ORU). QBI provides more flexibility to pursue collaborative programs and raise funding for the research.
The only ORU within UCSF focused on quantitative biology and collaborations around it.
Inherent to QBI’s core philosophy is partnership. We believe that the most efficient and productive way to advance is through key collaborations.
Cells are comprised of thousands of molecular machines, or protein complexes, that work together to ensure ...
Cells are comprised of thousands of molecular machines, or protein complexes, that work together to ensure healthy cell physiology. Identifying these machines and understanding how they function together can be used to generate maps of the cell which, in turn can be used to better understand disease states and provide novel therapies to fight them.
