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The QBI/SBI Seminar Series on molecular networks of cancer and other diseases aims to facilitate collaborative relationships between scientists from both the US and Ireland. QBI and UCD recently signed a 5-year MOU to reinforce the links between scientists in San Francisco and Dublin, and enhance their collaborative ability to strengthen scientific research and innovation. Through this agreement, scientists will work together to identify opportunities to promote cooperative biosciences research and training activities.
The series will launch on October 15 with Danielle Swaney from the University of California, San Francisco. Dr. Swaney’s lab is focused on using proteomics to enable biological discoveries. During her PhD training at the University of Wisconsin, she developed novel approaches to study phosphorylation signaling and leveraged these approaches during her postdoctoral training at the University of Washington to enable high-throughput characterization of crosstalk between phosphorylation and ubiquitin signaling. Now at UCSF, Dr. Swaney’s lab has been focused on the discovery of protein-protein interactions that regulate diseases, including cancer and SARS-CoV-2.
In her talk, "Identifying new roles for mutant PIK3CA signaling via protein-protein interaction analysis," she will outline a framework for elucidating tumor genetic complexity through multidimensional protein-protein interaction maps and apply this framework to prioritize cancer-enriched interactions that can serve as therapeutic targets.
Hosted by: Walter Kolch, SBI University College Dublin, Ireland
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