The BBC Graduate Program Seminar Series is presenting Barry Honig of Columbia University of February 27, 2020 at 12PM at the Helen Diller Cancer Center (Room 160). The Honig Lab investigates the physical properties of biological macromolecules and seeks to understand how they define biological activity within the cell. An essential component of their work is the development of algorithms and computational software for extracting accurate biological insights from three-dimensional structural information. These downloadable programs and web-based tools are based on conceptual insights developed in the lab into the functional nature of protein structure and have proved to be highly useful in facilitating novel insights into a variety of observed biological phenomena.

The Honig lab focuses on the following general themes:

• Molecular basis of cell-cell recognition
• Genome-wide structure-based prediction of protein-protein interactions
• Context-dependent cancer signaling pathways
• Host-pathogen interactions

Talk Title: The molecular basis of cell-cell recognition: Cellular patterning and nervous system wiring

Host: Tanja Kortemme