QBI - Seminar

Subcellular Renovation: Remodeling the Mitochondrial Inner-membrane

QBI presents a seminar with Luke Chao, Assistant Professor in the Department of Molecular Biology at the Massachusetts General Hospital and in the Department of Genetics at Harvard Medical School.

Dr. Chao obtained his undergraduate degree in Biochemistry from Brandeis. He pursued graduate studies in the lab of John Kuriyan at UC Berkeley, where he investigated the structure and function of the CaMKII holoenzyme. For his post-doctoral training with Stephen Harrison at Harvard Medical School, he studied flavivirus membrane fusion. His group at Mass General Hospital currently studies membrane remodeling in diverse contexts.

Organelle structure is tightly coupled to cell function. Mitochondrial membrane state plays a central role in cell signaling and metabolism. Dr. Chao will share his group's work using in vitro reconstitution to understand mechanisms regulating inner-membrane fusion, and in situ cryo-ET to understand remodeling of the mitochondrial inner-membrane folds, cristae.

Talk Title: Subcellular Renovation: Remodeling the Mitochondrial Inner-membrane

Hosts: Natalia Jura

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