About Us

MISSION STATEMENT

The Quantitative Biosciences Institute (QBI) fosters collaborations across the biomedical and the ph

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Cancer Cell
Map Initiatives

Host Pathogen
Map Initiatives

Psychiatric Cell
Map Initiatives

The Quantitative Biosciences Institute (QBI) fosters collaborations across the biomedical and the physical sciences, seeking quantitative methods to address pressing problems in biology and biomedicine. Motivated by problems of human disease, QBI is committed to investigating fundamental biological mechanisms, because ultimately solutions to many diseases have been revealed by unexpected discoveries in the basic sciences.

QBI EXECUTIVE COMMITTEE

The members of the QBI Executive Committee are experienced scientists and pioneers who are past and present directors of the institute. Their exceptional achievements are a sound but optimistic lense through which they see and guide the institute’s future aspirations.

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  • ANDREJ
    SALI

    Professor

    Develops methods for determining macromolecular assemblies structures

  • BRIAN
    SHOICHET

    Professor

    Investigates new chemical tools and techniques to perturb biology

  • DAVE
    AGARD

    Professor

    Focuses on the structural mechanisms of the Hsp90 molecular chaperone

  • SARAH
    NELSON

    Professor

    Focuses on quantitative analysis of novel MR metabolic imaging data

  • NEVAN
    KROGAN

    Professor - Director QBI

    Uses unbiased, systems approaches to understand complex biological problems

  • ANDREJ
    SALI

    Professor

    Develops methods for determining macromolecular assemblies structures

  • BRIAN
    SHOICHET

    Professor

    Investigates new chemical tools and techniques to perturb biology

  • DAVE
    AGARD

    Professor

    Focuses on the structural mechanisms of the Hsp90 molecular chaperone

  • SARAH
    NELSON

    Professor

    Focuses on quantitative analysis of novel MR metabolic imaging data

  • NEVAN
    KROGAN

    Professor - Director QBI

    Uses unbiased, systems approaches to understand complex biological problems

ORIGINS OF QBI

QBI was originally part of QB3, known as QB3-UCSF. QBI focuses on academic research and fostering co

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Cancer Cell
Map Initiatives

Host Pathogen
Map Initiatives

Psychiatric Cell
Map Initiatives

QBI was originally part of QB3, known as QB3-UCSF. QBI focuses on academic research and fostering collaboration between different science disciplines. In March of 2016, QBI became its own institute, and an Organized Research Unit (ORU). QBI provides more flexibility to pursue collaborative programs and raise funding for the research.

QBI ROLE WITHIN UCSF

The only ORU within UCSF focused on quantitative biology and collaborations around it.

"SOMEWHERE, SOMETHING INCREDIBLE IS WAITING TO BE KNOWN. "

CARL SAGAN

OUR PARTNERS

Inherent to QBI’s core philosophy is partnership. We believe that the most efficient and productive way to advance is through key collaborations.

CELL MAPPING INITIATIVES

Cells are comprised of thousands of molecular machines, or protein complexes, that work together to

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Cancer Cell
Map Initiatives

Host Pathogen
Map Initiatives

Psychiatric Cell
Map Initiatives

Cells are comprised of thousands of molecular machines, or protein complexes, that work together to ensure healthy cell physiology. Identifying these machines and understanding how they function together can be used to generate maps of the cell which, in turn can be used to better understand disease states and provide novel therapies to fight them.