Speakers
Natalia Jura, Kliment Verba, Kevan Shokat, Christopher Mathy, John Gordan, Abby Dernburg, Allen Liu, Roshanak Irannejad, Sarah Veatch, Scott Hansen, Saha Suvrajit, Juan Guan, Jared Toettcher, Zev Gartner, Jesse Zalatan, Daniel Schwartz, Danielle Swaney, Inna Kuperstein, Pedro Beltrao, Sourav Bandyopadhyay, Paige Haas, Neha Daga, Evangelia Petsalaki, Jeanne Stachowiak
JANUARY 28, 2020 DAY 1— Gladstone Institutes (1650 Owen St. San Francisco, CA 94158)
9:00 AM SYMPOSIUM BEGINS: Welcome Speech
Thematic Session One: Molecules and Structures
9:10 AM Natalia Jura, UC San Francisco: “Molecular Mechanisms of Receptor Kinase Signaling”
9:40 AM Kliment Verba, UC San Francisco: “Visualizing Novel Kinase States with cryoEM”
10:10 AM Kevan Shokat, UC San Francisco: “Oncogenic Mechanisms of Activating GTPases KRAS and GNAS and Their Inhibition” 10:40 AM Rapid Talk One: Christopher Mathy, UC San Francisco
10:50 AM Rapid Talk Two: John Gordan, UC San Francisco
10:55 AM Coffee Break
Thematic Session Two: Compartmentalization
11:25 AM Abby Dernburg, UC Berkeley: “Intracellular Pattern Formation Mediated by Phase Separation”
11:55 AM Allen Liu, University of Michigan: “Interplay Between CXCR4 Endocytosis, Signaling, and Post-translational Modifications”
12:25 PM Roshanak Irannejad, UC San Francisco: “GPCR Signaling from Internal Membrane Compartments”
12:55 PM Lunch with a presentation sponsored by Bruker
Thematic Session Three: At the Membrane
2:00 PM Sarah Veatch, University of Michigan: “Functional Heterogeneity in Cell Plasma Membranes”
2:30 PM Scott Hansen, University of Oregon: “Emergent Properties of MembraneProximal Signaling”
3:00 PM Rapid Talk Three: Saha Suvrajit, UC San Francisco
3:10 PM Rapid Talk Four: Juan Guan, UC San Francisco
3:20 — 5:00 PM Poster Session and Light Refreshments
DAY 2— Gladstone Institutes (1650 Owen St. San Francisco, CA 94158)
8:30 AM Registration
Thematic Session Four: Signaling Dynamics
9:00 AM Jared Toettcher, Princeton: “Optogenetics for Intracellular Codebreaking: How ERK Dynamics Control Gene Expression and Cell Fate”
9:30 AM Zev Gartner, UC San Francisco: “Building Tissues to Understand How Tissues Build Themselves”
10:00 AM Jesse Zalatan, University of Washington: “Scaffold-mediated Control of Competing Kinase Reactions in the Wnt Signaling Network”
10:30 AM Rapid Talk Five: Daniel Schwartz, UC San Francisco
10:40 AM Coffee Break
Thematic Session Five: Systems 11:15 AM Danielle Swaney, UC San Francisco: “Quantitative Multi-Dimensional Characterization of Protein-Protein Interactions in Cancer”
11:45 AM Inna Kuperstein, Institut Curie: “Multiomics Data-Driven Network-Based Signatures of Cancer for Mechanistic Explanation and Patient Stratification”
12:15 PM Pedro Beltrao, EMBL: “Global Cellular Studies of Kinase Signaling”
12:45 PM Rapid Talk Six: Paige Haas, UC San Francisco
12:55 PM Lunch
Thematic Session Six: Signaling Networks in Cancer
2:00 PM Sourav Bandyopadhyay, UC San Francisco: “Networks Mediating Receptor Tyrosine Kinase Activation and Drug Resistance in Cancer”
2:30 PM Neha Daga, EMBL: “Understanding T-Cell Regulatory Mechanisms in Autoimmune Diseases by Integrating Genetics and Epigenetics”
3:00 PM Evangelia Petsalaki, EMBL-EBI: “Dissecting Context-Dependent Cancer Signaling Processes Using CRISPR-based Approaches”
Confirmed Speakers:
Sourav Bandyopadhyay, UCSF
Pedro Beltrao, EMBL
Neha Daga, EMBL
Abby Dernburg, UC Berkeley
Zev Gartner, UCSF
Scott Hansen, University of Oregon
Roshanak Irannejad, UCSF
Natalia Jura, UCSF
Inna Kuperstein, Institut Curie
Allen Liu, University of Michigan
Evangelia Petsalaki, EMBL-EBI
Kevan Shokat, UCSF
Jeanne Stachowiak, UT Austin
Danielle Swaney, UCSF
Jared Toettcher, Princeton
Sarah Veatch, University of Michigan
Kliment Verba, UCSF
Jesse Zalatan, University of Washington