9:00 AM-7:00 PM
Co-organized by Drs. Aura Carreira, Bruno Goud and Nevan Krogan, the Quantitative Biosciences Institute (QBI), Institut Curie and the PSL-QLife Convergence Institute (PSL-QLife) present the inaugural 2019 QBI/Curie/PSL-QLife Symposium to be held in Paris September 5-6, 2019.
QBI seeks transformative results in biomedicine by supporting fundamental quantitative research in the biological sciences through significant collaborative efforts. Institut Curie, a private non-profit foundation recognized as a public-interest institution since 1921, is a major player in the fight against cancer, comprising France’s leading cancer research center and a world-class hospital group. PSL-QLife aims at shedding light on complex biological systems and processes using quantitative approaches at multiple spatial and temporal levels by fostering close collaboration between life scientists, chemists, physicists, computational scientists, mathematicians, and engineers.
In support of these missions, the 2019 QBI/Curie/PSL-QLife Symposium will focus on the collaborative potential between scientists from these institutions on the general topic of Quantitative Approaches to Cancer Research. Following the symposium, we look forward to putting in place a large collaborative agreement between UCSF, Institut Curie and PSL-QLife (comprising 8 research institutes: Institut Curie, Ecole Normale Supérieure, ESPCI, ChimieParisTech, IBPC, MinesParisTech, Collège de France and Institut Pasteur) to enable scientists on both sides to work together through exchange programs and opportunities for collaborative funding.
This workshop will be held on the Institut Curie Campus.
Thursday, September 5th, 2019
10.45 am Welcome Coffee at Green Café
11.10 am Opening by Nevan Krogan, Aura Carreira and Bruno Goud
Session 1: Systems Biology and Cancer
11.30 am Nevan Krogan, UCSF/QBI/Gladstone Institute
12.00 pm Emmanuel Barillot, Institut Curie/Q-life - "Some new challenges in computational molecular oncology"
12:30 pm Isha Jain, UCSF/QBI - "Systems Biology Approaches to Targeting Tumor Hypoxia"
1:00 pm Lunch at Green Café
3.00 pm Olivier Ayrault, Institut Curie - "Using quantitative proteomics to decipher the biology of medulloblastoma"
3:30 pm Sourav Bandyopadhyay, UCSF/QBI - "Mapping the networks that regulate oncogene dependency"
Session 2: Cell Invasion, Cell Movement and Motor Proteins
4.00 pm Anne Houdusse, Institut Curie/Q-life - "Control of force production by nanomotors in situ: from structural insights to mechanistic cell biology"
4.30 pm Emmanuel Farge, Institut Curie/Q-life - "Mechanotransduction in Mice Colon Tumorigenesis: Evolutionary Origins and Underlying Molecular Mechanism"
5.00 pm Coffee break at Green Café
5.30 pm Danijela Vignjevic, Institut Curie/Q-life - "Fibroblast-Induced Tumor Cell Budding: When Cell Mechanics Dictate Collective Cancer Cell Invasion"
6.00 pm Natalia Jura, UCSF/QBI - "Mechanisms for kinase signaling in cancer"
6:30 pm Matthieu Piel - Institut Curie/Q-life - "Breaching out of the duct: the role of nuclear deformation and nuclear envelope rupture in the switch of DCIS breast cancer cells to an invasive behavior"
8:30 pm Cruise dinner on the Seine
Friday, September 6th, 2019
9:15 am Welcome Coffee at Green Café
Session 3: Autophagy, Metal Transport, and Signaling
9.30 am Rushika Perera, UCSF/QBI - "Lysosome mediated remodeling of the cancer proteome"
10.00 am Raphael Rodriguez, Institut Curie/Q-life - "Roles of metals in cancer"
10.30 am Kevan Shokat, UCSF/QBI - "Drugging the Undruggable in Oncology"
11.00 am - Coffee break at Green Café
Session 4. Cell Fate and Survival Mechanisms
11.30 am Renata Basto, Institut Curie/Q-life - "Centrosome amplification favors survival and response to chemotherapy in ovarian cancer"
12.00 pm Davide Ruggero, UCSF/QBI
12:30 pm Leila Perie, Institut Curie/Q-life - "Single-cell fate in hematopoiesis"
1:00 pm Lunch at Green Cafe
Session 5. Targeting Cancer
2.00 pm Danielle Swaney, UCSF/QBI - "Multidimensional characterization of protein-protein interactions in cancer"
2.30 pm Jennifer Grandis – UCSF/QBI - "Leveraging the head and neck cancer proteome to improve therapy"
Session 6. Breast Cancer
3.00 pm Celine Vallot, Institut Curie/Q-life - "Heterogeneity of chromatin states in breast cancer"
3:30 pm Coffee break at Green Café
4:00 pm Aura Carreira, Institut Curie - "BRCA2: a model to understand genome integrity mechanisms and cancer predisposition"
5:00 Concluding remarks - closing
Practical information :
Location: Amphi C. BURG, 12 rue Lhomond 75005 Paris
Subscribe to our calendar and stay updated on the latest events.
You are now on our mailing list and will receive updates regularly.
Also, if you want to have your calendar updated automatically with QBI events, please download and double click on our .ics file listed below. It is compatible with Apple, Google, Facebook and Microsoft platforms.
Share event to your friends by email.
The event has been mailed to the given email address.