QBI - Symposium




1:00 PM-6:00 PM

The 2017 Cell Mapping Symposium will address research and technology advances in cell mapping as it relates to cancer, psychiatric disorders, and infectious disease.

The ability of a cell to respond to its environment depends on the actions of the proteins encoded by the DNA in the genome. However, most proteins don’t work alone. They work with other proteins in teams called complexes. The principles of “cell mapping” are to figure out which proteins work together in complexes. Mapping can be done in different disease states or in the presence of different chemical drugs. To accomplish these goals, researchers augment these cell maps with genetic maps to derive quantitative insights into how biological functions of cells can be restored.

One of the main objectives of this symposium is to discuss technological advances in extracting mechanistic insight from these large genome sequencing projects. These efforts include using proteomic, biochemical, genetic, and structural biology approaches to generate cellular maps that can be used to interpret this genomic data from a variety of different disease areas. 

The 2017 Cell Mapping Symposium, will be held over 2 days, September 13 and September 14, 2017, at Gladstone Institutes in San Francisco’s Mission Bay neighborhood.  The symposium will start at 1:00 pm on September 13th, at the Mahley Auditorium and end at 4:30 pm on September 14th. Confirmed speakers for the symposium are listed below. 

Photo of the Remarkables mountain range in Queenstown, New Zealand.

Confirmed Speakers:

Dave Agard, UC San Francisco - "Using CryoEm to understand dynamic protein complexes"

Cori Bargmann, Chan-Zuckerberg Science & The Rockefeller University  - “Diversity of cellular function in the nervous system”

Michael Boutros, DKFZ - "Mapping genetic interaction networks (in cancer cells)"

Jasmin Fisher, University of Cambridge & Microsoft Research - "Deconstructing Cancer Networks Using Executable Biology"

Jeffery Cox, UC Berkeley - "Architecture of Mce lipid transport systems that connect inner and outer bacterial membranes"

Jennifer Grandis, UC San Francisco - "Targeting the PIK3CA mutant interactive in Head and Neck Cancer"

Rick Horwitz, Allen Institute - "Integrated spatial-temporal stem cell biology - a next step in the post genomic era"

Trey Ideker, UC San Diego - Title TBD

Peter Jackson, Stanford University -  "A KRAS physical and genetic interaction network reveals new cancer susceptibilities"

Martin Kampmann, UC San Francisco - "Mapping neuronal cell biology in health and disease with CRISPRi and CRISPRa" 

Nevan Krogan, Gladstone Institutes & UC San Francisco - Title TBD

Kasper Lage, Massachusetts General Hospital, Stanley Center at the Broad Institute & Harvard Medical School - “Large-scale protein-protein interaction experiments of schizophrenia risk genes in human neurons coalesce GWAS loci into unexpected pathways"

Joana Loizou, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences -"Rebalancing DNA repair pathways in disease"

Kathryn Miller-Jensen, Yale University - Title TBD

Clodagh O' Shea, Salk Institute - Title TBD

Teresa Przytycka, NCBI, NIH - "New methods to uncover properties of mutational landscape in cancer"

Ben Raphael, Princeton University - Title TBD

Andrej Sali, UC San Francisco - Integrative structural biology

Jeremy Willsey, UC San Francisco - "Identifying Convergent Molecular Pathways in Autism"

Laura Van’t Veer, UC San Francisco - "Mapping treatment response to biological networks: the I-SPY 2 TRIAL"

Mark Von Zastrow, UC San Francisco - "Spatiotemporal dynamics of protein interaction networks in living cells"

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