QBI and Rezo Therapeutics present Xiulei Mo, PhD, an Assistant Professor in the Department of Pharmacology and Chemical Biology at Emory University School of Medicine. The long-term goal of Dr. Mo's research is to understand the molecular basis underlying tumor initiation, progression and drug resistance, and to bridge the gap between vast cancer genomic dataset and unmet clinical need. A major focus of Dr. Mo's research is to understand and target "undruggable" loss-of-function tumor suppressor genes through a systems biology approach to identify rewired cell signaling networks and vulnerabilities, and through a chemical biology approach to discover small molecules to restore tumor suppressor function in cancer.

In this seminar, Dr. Mo will talk about his recent research on systematic discovery of cancer driver mutation mediated neo-protein-protein interactions, and showcase how to leverage the vast network biology data for therapeutic innovation.

Talk Title: Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

Host: Sourav Bandyopadhyay